I'm sorry if this offends some people, but the obvious answer is drugs. Marijuana, LSD, ecstasy, magic mushrooms, cocaine, heroin, opium. They all alter a person's perception of the world around them, and their position in it. For instance, if someone is stressed out, they might smoke pot to relax because it makes things seem a lot less pressing and important. LSD and magic mushrooms both alter what things look, smell, taste, and sound like. Ecstasy convinces you that the best thing to do at the time is have as much sex as possible. Cocaine makes a person really paranoid, and they think they can't trust anybody. Heroin induces euphoria, and one feels like life is the best it's ever been for a while.
By the way, before anybody gets the wrong idea, I'm not some sort of junkie drug lord. I know all this from stories and common knowledge and, in some cases, research.
There are six drugs listed above. Say you took one every day of the week, with Monday being a day for sobriety. Your reality would be different every single day.
Another thing that can change people's perspectives about the world and their lives is death. When people have a near-death experience, they tend to change their perspectives on what's important in their lives. They may start being overly cautious and pious in an attempt to hold off their inevitable death. Some people have a near-death experience and decide to start living their lives without any thought of the consequences. They might start doing drugs and hooking up with various partners and buying extravagant things that they've always desired. The death of a loved one can have the same effects.

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